career

Avergen Pharmaceuticals is a science-led, startup company. We are committed to best practices in corporate governance and believes that such principles are critical to our success.

Current vacancies

We are looking for a master student. He or she should be enthusiastic for drug discovery and ready to work in a startup company. 

Please contact Dr. Yildiz: marius.yildiz@avergen.com


 

Master Thesis or Rotation Project

 

(beginning asap)

 

 

 

Avergen Pharmaceuticals

 

AND

 

Biomedical Center, Physiological Chemistry

 

AG Ladurner

 

 

“Curing Huntington’s disease with novel medicines”

 

Cellular profiling of novel, innovative disease modulating compounds

 

Background

Huntington’s disease is caused by toxic accumulation of the HTT protein. Our novel compounds impact this disease mechanism to provide a curative treatment for this life-threatening disease.

In this thesis of rotation, we offer you to participate and shape a project that shines

light on the cellular cure to Huntington’s disease.

 

What will you be working on?

You will perform work on animal tissues and cell cultures to decipher

the molecular consequences of small-molecule mediated disease modification.

Cutting-edge academic science within the LMU department of physiological

chemistry will be combined with support from Avergen Pharmaceuticals – sharing

deep expertise in drug development and cellular disease modulation.

 

This project aims to answer: How do active small molecules impact cellular aspects of Huntington’s disease?

 

By using powerful tools such as compound treatment, genetics, live-cell imaging and cell-based assays, your project will provide valuable insights into novel and disease-relevant mechanisms, as the basis of your high-ranking publication.

 

What techniques will you use?

• IHC and IF staining of mouse disease tissue

• Mammalian cell culture and transfections

• Drug sensitivity and gene expression assays

• Fluorescence microscopy and quantitative live-cell imaging

 

Contact

· If interested, please contact Marius Yildiz (CEO of Avergen Pharmaceuticals; marius.yildiz@avergen.com)

· You can also stop by and visit us in the IZB House 7, 2nd floor or the LMU Biomedical Center (room N.B.02.009).

 

 Compensation provided